The most frequent reason people seek medical attention is due to pain. It is one of the most common symptoms of disease/illness and can significantly interfere with a person’s quality of life. There are various classifications of pain which include nociceptive (tissue damage), neuropathic (nerve damage), psychogenic (pain caused, increased, or prolonged by mental, emotional, or behavioral factors), and breakthrough pain to name a few. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are commonly prescribed medications for nociceptive and neuropathic pain pathways. Oral NSAIDs often are accompanied with side effects such as stomach upset, gastritis, dry mouth, fatigue, dizziness, and drowsiness. Long term oral NSAID use could possibly lead to ulcers, gastrointestinal bleeds, kidney, and/or liver impairment, dysfunction, or disease.
There is a therapeutic alternate delivery to oral NSAIDs. Here at University Compounding Pharmacy (UCP), our highly trained pharmacists have developed a variety of topical NSAID cream and gel formulations. In Europe, topical preparations of NSAIDs have been used for years and have recently grown in popularity in the US. This alternative form of pain relief can be applied directly to the site of the pain and absorbed through the skin. Such dosage forms may bypass the gastrointestinal system and do not undergo first-pass hepatic (liver) metabolism; therefore, providing optimal results with less side effects commonly associated with oral administration.
All formulations are customized per prescription to meet the unique needs of each patient. For most who suffer from chronic pain, a variety of medications are used to help alleviate the symptoms associated with their condition. Optimal treatment may involve the use of medications that possess pain-relieving properties, including some antidepressants, anticonvulsants, antiarrhythmics, and anesthetics. Our topical pain preparations may include but are not limited to a combination of Ketoprofen, Gabapentin, Amitriptyline, Lidocaine, and Cyclobenzaprine. Compounding allows the pharmacist to combine these pain medications into a single topical formulation which provides added convenience and better compliance for the patient.
At University Compounding Pharmacy, we work together with your physician to solve problems by customizing medications that meet the specific needs of each individual. Please contact our compounding pharmacists to discuss the dosage form, strength, and medication or combination that is most appropriate for you.